Lancashire halted a run of three Royal London One-Day Cup defeats by recording a 101-run win over Derbyshire with nearly 10 overs to spare at the 3aaa County Ground.
Derbyshire were unbeaten in three matches but a target of 301 proved beyond them and their former paceman Wayne White took 4-33 as they were bowled out for 199, skipper Wayne Madsen top-scoring with 49.
Lancashire's total of 300 for eight, which was their highest against Derbyshire in one-day cricket, was built around half-centuries from Ashwell Prince, Karl Brown, Alex Davies and Steven Croft.
The damage could have been more severe without Tony Palladino best limited-overs figures of 5-49.
The Falcons lost early wickets and when Madsen was fifth out to White with 200 still needed, the game was almost up. To complete a miserable day for Derbyshire, 19-year-old seamer Tom Taylor suffered what appeared to be a serious ankle injury.
Footitt gone! White finishes with 4-33 and Derbyshire are 199 all out. He's bowled. Taylor won't bat. 101-run win.
— Lancashire CCC (@LancsCCC) August 7, 2014
Lancashire's innings started slowly with only 49 coming from the first 10 overs powerplay for the loss of Australia batsman Usman Khawaja, who made 31 from 28 balls against his former county before Mark Footitt found some late movement and bounce to have him caught behind.
Taylor injured his left ankle two balls into his sixth over and had to be helped off the field, while Lancashire gradually increased the tempo with Prince and Brown adding 61 in 15 overs.
Prince was bowled for 57 trying to sweep David Wainwright and Brown also failed to go on when he was caught behind for 59 off a bottom-edged pull against Palladino in the 32nd over.
Lancashire lost skipper Paul Horton (19) in Palladino's next over when he was caught at point off a ball that stopped on him, but Davies lifted Footitt over the wicketkeeper's head for the first six of the innings as he and Croft accelerated in the last 10 overs.
Croft drove and pulled Wes Durston for successive sixes before Palladino halted the charge by having him caught at deep square leg for 51 from 42 balls, going on to york Davies for 53 with the next delivery.
AUDIO | Listen to post-match reaction from Tony Palladino who claimed career-best 5-49 #DERvLAN#P2bDhttps://t.co/9q6kGeo3IX
— Derbyshire CCC (@DerbyshireCCC) August 7, 2014
Derbyshire's chase started badly when the dangerous Durston was lbw playing back to Tom Bailey, who struck again by tempting Scott Elstone into a wild drive at a wide ball with only 28 on the board.
When Billy Godleman also fell to a reckless cut at Jordan Clark and Marcus North top-edged to backward point trying to pull White, Derbyshire's hopes rested with Madsen who moved smoothly to 49 from 37 balls.
But when he tried to launch White over the deep square leg boundary and picked out Brown it signalled the end of the home side's chances and, although Alex Hughes straight-drove Simon Kerrigan for six, White completed an efficient display by the visitors with 57 balls to spare.